Ångström AI

About

Ångström AI is a Cambridge University spinout founded in 2024 by Javier Antoran, José Miguel Hernández-Lobato, and Laurence Midgley that develops GenAI-based molecular simulations to substitute wet lab experiments in pre-clinical drug development. The company combines quantum-accurate physics models with generative AI to enable biotech and pharmaceutical clients to verify drug candidate efficacy and safety using computer simulations that match wet lab accuracy while being over 100x faster. Ångström AI uses the MACE (multi-atomic cluster expansion) physics model to accurately reproduce quantum-mechanical interactions, with recent breakthrough research showing their simulations are the first to provide accuracy comparable to lab experiments when estimating hydration-free energies. The company accelerates MACE simulations using diffusion models to make them computationally affordable, backed by Y Combinator and founded by a team of 2 PhDs and 2 Professors from Cambridge who combined breakthroughs in quantum-accurate physics modeling with generative AI. 2025 Developments: The company continues to enhance its quantum software platform and developer tools in 2025. Focus remains on improving algorithm efficiency and expanding use case applications. Active engagement with the quantum developer community drives product evolution.

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Key People

Javier Antoran (Co-founder), José Miguel Hernández-Lobato (Co-founder, Chief AI Officer), Laurence Midgley (Co-founder)